Study Of The Synthesis Of Losartan Potassium.

Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure. It is also used for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth. It may be used alone or in addition to other blood pressure medication. Up to six weeks may be required for the full effects to occur.

Losartan potassium 124750-99-8 route of synthesis, Losartan potassium chemical synthesis methods, Losartan potassium synthetic routes ect.

Losartan: 7 things you should know - Drugs.com.

Improved processes using primary, secondary and tertiary alcohols and with safer mode of introduction of the reagent and reaction conditions are described. Further, the process of manufacture of Losaratan potassium by use of alkali metal salt such as Potassium carbonate is disclosed. A process for preparation of the polymorphic Form I of Losartan potassium is also disclosed herein.Losartan may interact with a few medications and herbal supplements so check with your doctor or pharmacist before starting losartan or before starting any new medicines. Also, check with your pharmacist before taking over-the-counter medicines such as anti-inflammatories such as diclofenac (e.g. Voltaren Rapid), ibuprofen (e.g. Nurofen), naproxen (e.g. Naprogesic).Losartan Potassium, as a biphenyltetrazole angiotensin II receptor antagonist, was developed by Merck Co. and ratified by FDA for antihypertensive, with the characterstics of long-lasting, good tolerance and high receptor-selectivity.The project aims to study synthesis of Losartan Potassium.


Losartan tablets are available in 25 mg, 50 mg, or 100 mg. The usual starting dose is 50 mg, but people treated with diuretics may be started off with 25 mg, once or twice daily.Losartan simple presentation 1. Name: Danny Liew Teck Yee 2. Objective To learn what is Losartan To describe the mechanism of action of Losartan To state the adverse effects of Losartan.

Losartan suspension can be refrigerated for up to 4 weeks. Your doctor may require you to see him or her regularly for monitoring of your blood pressure, kidney function, or electrolytes. If you are a woman capable of having children, you should ensure you use adequate contraception to avoid getting pregnant while on losartan, as it can be harmful to a developing baby.

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A process for the synthesis of Losartan Postassium by reacting Trityl Losartan in a primary alcohol with potassium tertiary alkoxide.

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Losartan is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain.

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Losartan is widely used in clinics to treat cardiovascular related diseases by selectively blocking the angiotensin II type 1 receptors (AT1Rs), which regulate the renin-angiotensin system (RAS). Therefore, monitoring the physiological and pathological biodistribution of AT1R using positron emission tomography (PET) might be a valuable tool to assess the functionality of RAS.

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Losartan 50 MG Tablet belongs to the angiotensin II receptor antagonists group of drugs. It prevents the blood vessels in your body from narrowing, thus lowering your blood pressure and improving the blood circulation. This medication has the ability to lower the possible risk of a stroke in people suffering from any heart condition. Apart from that, it can also slow down kidney damage among.

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Losartan is used in conditions, such as, elevated blood pressure, increased work load on the heart, and heart failure, as it reduces the blood pressure and work load on the heart. Also, Losartan, by inhibiting narrowing of blood vessels, helps to keep them open and patent, and consequently lead to improved blood flow to the vital organs, such as, heart, brain and kidneys.

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With losartan, an interaction can develop if the drug is taken with medicines such as potassium supplements, potassium-sparing diuretics, or nonsteroidal anti-inflammatory drugs. Besides causing your body to metabolize the medicines differently than intended, drug interactions with losartan may also cause excessive levels of drugs in your body or extremely low blood pressure.

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Losartan is an angiotensin II receptor antagonist.This type of medicine is used to lower high blood pressure and needs to be taken daily. If you have been taking losartan for at least three months, Zava can issue a repeat prescription, saving you a trip to your local doctor. Please note that you will still need to see your GP for regular check-ups.

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Losartan can be taken by adults aged 18 years and over. Children aged 6 years and older can take it, but only to treat high blood pressure. Your doctor may prescribe losartan if you've tried taking similar blood pressure-lowering medicines such as ramipril and lisinopril in the past, but had to stop taking them because of side effects such as a dry, irritating cough.

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Losartan is used to treat high blood pressure and to help protect the kidneys from damage due to diabetes.It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart.Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Losartan belongs to a class of drugs called angiotensin receptor blockers (ARBs).

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